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Key Documents

194751

Sigma-Aldrich

N-tert-Butylhydroxylamine hydrochloride

≥98%

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About This Item

Linear Formula:
(CH3)3CNHOH · HCl
CAS Number:
Molecular Weight:
125.60
Beilstein:
3546053
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

≥98%

form

solid

mp

183-185 °C (lit.)

SMILES string

Cl.CC(C)(C)NO

InChI

1S/C4H11NO.ClH/c1-4(2,3)5-6;/h5-6H,1-3H3;1H

InChI key

DCSATTBHEMKGIP-UHFFFAOYSA-N

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Application

N-tert-Butylhydroxylamine hydrochloride was used in spin trapping of short-lived radicals. It was also used in the synthesis of α-ketoamides and 3-spirocyclopropanated 2-azetidinones.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Hyun Jeong Kim et al.
Redox report : communications in free radical research, 10(6), 287-293 (2006-01-28)
Heat shock may increase oxidative stress due to increased production of reactive oxygen species and/or the promotion of cellular oxidation events. Therefore, compounds that scavenge reactive oxygen species may regulate heat shock-induced cell death. Recently, it has been shown that
Yu-Kyung Kim et al.
Clinical hemorheology and microcirculation, 40(4), 315-324 (2009-01-08)
Irradiation has been shown to induce biochemical changes in stored red blood cells (RBCs) and to generate reactive oxygen species (ROS). This study evaluated the hemorheological properties, the degree of lipid peroxidation and the oxidative susceptibility of irradiated RBCs. Furthermore
A New Three-Component Cascade Reaction to Yield 3-Spirocyclopropanated?-Lactams.
Zanobini A, et al.
European Journal of Organic Chemistry, 2006(5), 1251-1255 (2006)
On the anti-aging activities of aminoguanidine and N-t-butylhydroxylamine.
A R Hipkiss
Mechanisms of ageing and development, 122(2), 169-171 (2001-02-13)
Ludmila A Voloboueva et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 21(14), 4077-4086 (2007-07-28)
Age-related macular degeneration (AMD) is the leading cause of severe visual impairment in the elderly in developed countries. AMD patients have elevated levels of iron within the retinal pigment epithelia (RPE), which may lead to oxidative damage to mitochondria, disruption

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