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Y0000402

Pyrantel embonate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Pyrantel pamoate, 1-Methyl-2-(2-[2-thienyl]ethenyl)-1,4,5,6-tetrahydropyrimidine compound with 4,4′-methylenebis(3-hydroxy-2-naphthoic acid), Pyrantel embonate

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About This Item

Linear Formula:
C11H14N2S · C23H16O6
CAS Number:
Molecular Weight:
594.68
Beilstein:
9034755
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

pyrantel

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CN1CCCN=C1\C=C\c2cccs2.OC(=O)c3cc4ccccc4c(Cc5c(O)c(cc6ccccc56)C(O)=O)c3O

InChI

1S/C23H16O6.C11H14N2S/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2,4-6,9H,3,7-8H2,1H3/b;6-5+

InChI key

AQXXZDYPVDOQEE-MXDQRGINSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Pyrantel embonate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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[The action of pyrantel pamoate in the therapy of helminth infestations].
C Fossati
La Clinica terapeutica, 93(6), 713-717 (1980-06-30)
Christian Schwartz et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(48), E5169-E5177 (2014-11-19)
Basophils orchestrate protection against reinfections with gastrointestinal helminths and ticks, but the underlying mechanisms remain elusive. We investigated the role of Fc receptors on basophils, the antibody isotypes IgG1 and IgE, and basophil-derived IL-4/IL-13 during challenge infections with Heligmosomoides polygyrus
Tara E Paterson et al.
Veterinary parasitology, 205(3-4), 687-696 (2014-09-30)
Advocate(®) (2.5% moxidectin+10% imidacloprid) (Bayer HealthCare, Leverkusen, Germany) is a multiparasiticidal spot-on authorized for treating canine demodicosis in many countries. This blinded, randomized three-phase clinical trial compared its efficacy employing different dosing regimens with that of ivermectin. In the blinded
Pyrantel pamoate for pinworm infestation.
G Van Riper
American pharmacy, NS33(2), 43-45 (1993-02-01)
Oxantel pamoate-albendazole for Trichuris trichiura infection.
Kosuke Yasukawa
The New England journal of medicine, 370(20), 1952-1952 (2014-05-16)

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