SYNPLE-M001

Reagent-cartridge Mitsunobu

Synple

• Synonym(s): Synple 2
• MDL number: MFCD32903606
• UNSPSC Code: 12161503
• NACRES: NA.22

Properties

• Quality Level: 100
• parameter: up to 0.5 mmol scale

Description

General description

Reagent-cartridge Mitsunobu is a reagent cartridge for the Synple 2 Automated Synthesizer that enables the dehydrative coupling of primary alcohols and a variety of pronucleophiles. The cartridge contains all necessary reagents to perform the Mitsunobu transformation. The Synple platform eliminates the tedious removal of the Ph₃PO byproduct.

Scale: up to 0.5 mmol
Compatible alcohols: primary, secondary
Compatible nucleophiles: phenols, carboxylic acids, tosyl amides, hydrazones, phthalimides

Cartridge contents:

• Supported triphenylphosphine
• DTBAD (di-tert-butyl azodicarboxylate)
• SCX (for purification)
• Supported carbonate (scavenger)

Learn more about the Synple automated synthesis platform.

Features and Benefits of Synple Platform

• Time savings - pre-installed protocols have been highly optimized, which obviates the need for the user′s own reaction development and optimization
• Easy to use - protocols are loaded by simply scanning the cartridge; does not requires any programming knowledge
• Safety - all chemicals are contained in the system, minimizing the user′s exposure
• Set-up reaction in less than 5 minutes
• Small footprint
• Plug & Play system - simple installation
• Reaction temperatures from 25 °C - 80 °C
• Cartridges available for many different reactions
• Prefilled with all required reagents
• RFID chip containing optimized reaction protocol

Other Notes

An integrated console for capsule-based, automated organic synthesis

Legal Information

Product of Synple Chem AG

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable