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P5239

Supelco

Pinocembrin

analytical standard, ≥95.0% (HPLC), solid

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About This Item

Empirical Formula (Hill Notation):
C15H12O4
CAS Number:
480-39-7
Molecular Weight:
256.25
MDL number:
MFCD06858345
UNSPSC Code:
41116107
PubChem Substance ID:
329820219
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥95.0% (HPLC)

form

solid

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

194-195 °C (lit.)

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

OC1=C(C(C[C@@H](C2=CC=CC=C2)O3)=O)C3=CC(O)=C1

InChI

1S/C15H12O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-7,13,16-17H,8H2/t13-/m0/s1

InChI key

URFCJEUYXNAHFI-ZDUSSCGKSA-N

General description

Pinocembrin is a major flavonoid molecule, isolated from a variety of plants such as Euphorbia, Sparattosperma leucanthum, Populus, Eucalyptus, Pinus heartwood, etc. It exhibits antitumor, antimicrobial, anti-inflammatory and antioxidant properties.
Anti-inflammatory.

Application

Pinocembrin has been used as a standard in the determination of pinocembrin in propolis extract, analyzed using ultraviolet-visible spectrophotometry (UV-Vis).
Pinocembrin may be used as an analytical reference standard for the quantification of the analyte in honey samples using capillary electrophoresis technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Caution

Protect from light.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV8464
MKCT2814
MKCR6791
MKCQ1726
MKCR6793

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Rui Liu et al.
BMC medicine, 10, 105-105 (2012-09-20)
It is known that amyloid-β peptide (Aβ) plays a pivotal role in the pathogenesis of Alzheimer's disease (AD). Interaction between Aβ and the receptor for advanced glycation end products (RAGE) has been implicated in neuronal degeneration associated with this disease.
Pinocembrin: a novel natural compound with versatile pharmacological and biological activities
Rasul A, et al.
BioMed Research International, 2013(1-2), 71-78 (2013)
Jia Le Lee et al.
Antiviral research, 167, 13-24 (2019-04-09)
Zika virus (ZIKV) is a mosquito-borne virus that has garnered a lot of attention in recent years, due to the explosive epidemic from 2014 to 2016. Since its introduction in the Americas in late 2014, ZIKV has spread at an
Capillary electrophoresis as an alternative to HPLC for determination of honey flavonoids
Delgado.C, et al.
Chromatographia, 38(1-2), 71-78 (1994)
Xu Yang et al.
Biomolecules, 8(2) (2018-06-21)
Pinocembrin is a natural flavonoid compound which is capable of antioxidant, antibacterial, anti-inflammatory, and antineoplastic activities. The present study aimed to enhance the solubility and antioxidant activities of pinocembrin by complex formation with lecithin. The physicochemical characteristics of pinocembrin⁻lecithin complex
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Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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