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Key Documents

P3750000

Propyphenazone

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

4-Isopropylantipyrine, 1,2-Dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-3H-pyrazol-3-one, 1,2-Dihydro-4-isopropyl-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one, Isopropylphenazone, Propyphenazone

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About This Item

Empirical Formula (Hill Notation):
C14H18N2O
CAS Number:
Molecular Weight:
230.31
Beilstein:
204533
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

propyphenazone 

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

O=C1C(C(C)C)=C(C)N(C)N1C2=CC=CC=C2

InChI

1S/C14H18N2O/c1-10(2)13-11(3)15(4)16(14(13)17)12-8-6-5-7-9-12/h5-10H,1-4H3

InChI key

PXWLVJLKJGVOKE-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Propyphenazone EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Ngoc Han Tran et al.
Journal of hazardous materials, 171(1-3), 1051-1057 (2009-07-21)
The biodegradation of 10 selected pharmaceuticals by enriched nitrifier cultures with ammonia oxidizing activity of 30mg NH(4)-N/gMLVSSh was investigated under various initial operating conditions such as in the presence of different growth substrates and inhibitors. The enriched nitrifier culture showed
Liulin Deng et al.
Journal of mass spectrometry : JMS, 45(7), 734-739 (2010-07-14)
Two analgesic and anti-inflammatory drugs, antipyrine and propyphenazone, were investigated with infrared laser desorption/tunable synchrotron vacuum ultraviolet (VUV) photoionization mass spectrometry (IR LD/VUV PIMS) and theoretical calculations. Mass spectra of the two drugs were measured at various photon energies. Fragment
Rade Injac et al.
Journal of chromatographic science, 46(2), 137-143 (2008-03-28)
A method is described for quantitating caffeine, theobromine, theophylline, paracetamol, propyphenazone, acetylsalicylic acid, salicylic acid, and codeine phosphate in corresponding real samples of food, beverages, natural products, pharmaceuticals, and cosmetic preparations by micellar electrokinetic capillary chromatography. The separation is carried
Jian-Guo Jiang et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 48(1), 94-97 (2013-04-23)
This paper reports the establishment of a method for rapid identification 15 effective components of anti common cold medicine (paracetamol, aminophenazone, pseudoephedrine hydrochloride, methylephedrine hydrochloride, caffeine, amantadine hydrochloride, phenazone, guaifenesin, chlorphenamine maleate, dextromethorphen hydrobromide, diphenhydramine hydrochloride, promethazine hydrochloride, propyphenazone, benorilate
Ashwini Ojha et al.
Bioanalysis, 1(2), 293-298 (2009-05-01)
Dipyrone (metamizole) is a nonsteroidal anti-inflammatory drug used as an analgesic and antipyretic in both pediatric and adult patients. Dipyrone hydrolyses to 4-methylaminoantipyrine (MAA) in the stomach before absorption. There are several HPLC methods available for analysis of MAA from

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