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AB2201

Anti-mPER1 (residues 6-21) Antibody

serum, from rabbit

Synonym(s):

Circadian clock protein PERIOD 1, Circadian pacemaker protein Rigui, Period, drosophila, homolog of period 1, period (Drosophila) homolog 1, period homolog 1 (Drosophila)

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
18
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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse, rat

technique(s)

western blot: suitable

GenBank accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

mouse ... Per1(18626)

General description

136 kDa
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known. Alternative splicing has been observed in this gene; however, these variants have not been fully described.

Application

Detect mPER1 (residues 6-21) using this Anti-mPER1 (residues 6-21) Antibody validated for use in WB.
Immunohistichemistry:
Tested on whole brain (SCN; peak staining at CT/ZT12). Optimium working dilutions need to be determined by end used.

Biochem/physiol Actions

Cat. # AB2201 will recognize the N-terminus of mPER1.
May react with Drosophila, Arvicanthis niloticus and Mesocricetus auratus based on sequence homology. Reactivity with other species has not been tested.

Analysis Note

Routinely tested by western blot on human brain lysate

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services

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Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

serum

antibody form

serum

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

UniProt accession no.

O35973

UniProt accession no.

O54943

UniProt accession no.

O15055

UniProt accession no.

Q9H313

species reactivity

human, mouse, rat

species reactivity

mouse, rat

species reactivity

human, mouse, rat

species reactivity

human


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Storage Class

10 - Combustible liquids

wgk

WGK 1



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Questions

  1. What is the concentration ?

    1 answer
    1. This antibody is supplied in the form of unpurified polyclonal rabbit serum, for which the exact specific antibody concentration is not determined. However, for polyclonal antiserum, the specific antibody concentrations could range from 1-10 mg/mL serum, but typically range from 1–3 mg/mL serum.

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