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Key Documents

1.08489

Sigma-Aldrich

Urease

lyophilized 5 U/mg EC 3.5.1.5

Synonym(s):

Urease Enzyme

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About This Item

UNSPSC Code:
12352204
NACRES:
NA.21
Pricing and availability is not currently available.

form

solid

pH

6.0-7.0 (20 °C, 5 g/L in H2O, slurry)

bulk density

410 kg/m3

storage temp.

2-8°C

General description

Urease (urea amidohydrolase; EC 3.5.1.5) is a nickel-dependent metalloenzyme that is found in various plants, bacteria, fungi, algae, and even some invertebrates.

Biochem/physiol Actions

Urease catalyzes the hydrolysis of urea to ammonia and CO2. It is implicated in the development of enzymology and heme protein chemistry. Bacterial urease acts as a virulence factor and is involved in the pathogenesis of hepatic coma, peptic ulceration, and pyelonephritis.

Analysis Note

Activity: ≥ 5 U/mg
Suitability for determination of urea: passes test

Pictograms

Exclamation markHealth hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 1


Certificates of Analysis (COA)

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Questions

1–3 of 3 Questions  
  1. Hi Team, Is there any information available on the below unit definition? Thank you. Regards, Sahana S Our email address has moved to [email protected].

    1 answer
    1. Dr. Timm Schlegelmilch from Life Science provided the following information: For 1.08489, 1U is defined as the amount of enzyme that catalyzes 1 µmol urea to ammonia and CO2 per minute, at 25°C and pH 8.0. Therefore, with the current specification of > 5 U/mg, it is guaranteed that each milligram of the product can catalyze the reaction of 5 µmol urea per minute.

      Helpful?

  2. What is the molecular wiegth of this product?

    1 answer
    1. The molecular weight of this product is 545 kDa.

      Helpful?

  3. Hello. I need to know the molecular weight of urease enzyme(1.08489), and It is not written in the documents. I would be grateful if you could help me 🙏.

    1 answer
    1. The molecular weight is 545 kDa.

      Helpful?

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