Skip to Content
Merck
All Photos(1)

Key Documents

700172P

Avanti

cholesterol-d6

Avanti Research - A Croda Brand, powder

Synonym(s):

cholesterol-d6

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C27H40D6O
CAS Number:
Molecular Weight:
392.69
UNSPSC Code:
41141804
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (700172P-10mg)

manufacturer/tradename

Avanti Research - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

General description

Cholesterol-d6 is a deuterium labelled cholesterol. Ring labelled D6-cholesterol forms D6-steroidal glycoalkaloids (SGA).
Cholesterol-d6 is the deuterated cholesterol with deuteration in ring.

Application

Cholesterol-d6 is suitable for its use as a synthetic lipid standard, for cholesterol determination.
Cholesterol-d6 is used as a standard to detect cholesterol concentration using chromatography technique. It is also used to measure the percentage of cholesterol absorption by intravenously administrating into experimental animals.
Cholesterol-d6 may be used as an internal standard in
  • electrospray ionization tandem mass spectrometry (ESIMS/MS)
  • gas chromatography–mass spectrometry (GC-MS)
  • for spiking lipid extracts from Drosophila for liquid chromatography–mass spectrometry (LC-MS)

Biochem/physiol Actions

Cholesterol-d6 rich liposomes are used in understanding the kinetics of reverse cholesterol transport in lymphatic and aorta. It is used in the generation of stratum corneum (SC) lipid model systems for deuteration based neutron diffraction studies. Use of Cholesterol-d6 as a diet supplement has enabled the understanding cholesterol metabolism in the blood brain barrier.

Packaging

5 mL Amber Glass Screw Cap Vial (700172P-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 1


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin
Singh K, et al.
Nature Communications, 9(1), 3425-3425 (2018)
Effects of a disrupted blood-brain barrier on cholesterol homeostasis in the brain
Saeed AA, et al.
The Journal of Biological Chemistry, 289(34), 23712-23722 (2014)
The tumor suppressor TERE1 (UBIAD1) prenyltransferase regulates the elevated cholesterol phenotype in castration resistant prostate cancer by controlling a program of ligand dependent SXR target genes
Fredericks WJ, et al.
Testing, 4(7), 1075-1075 (2013)
Central leptin regulates total ceramide content and sterol regulatory element binding protein-1C proteolytic maturation in rat white adipose tissue
Bonzon-Kulichenko E, et al.
Endocrinology, 150(1), 169-178 (2008)
Conversion of exogenous cholesterol into glycoalkaloids in potato shoots, using two methods for sterol solubilisation
Petersson EV, et al.
PLoS ONE, 8(12), e82955-e82955 (2013)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service