700172P
Avanti
cholesterol-d6
Avanti Research™ - A Croda Brand, powder
Synonym(s):
cholesterol-d6
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Recommended Products
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (700172P-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
General description
Cholesterol-d6 is a deuterium labelled cholesterol. Ring labelled D6-cholesterol forms D6-steroidal glycoalkaloids (SGA).
Cholesterol-d6 is the deuterated cholesterol with deuteration in ring.
Application
Cholesterol-d6 is suitable for its use as a synthetic lipid standard, for cholesterol determination.
Cholesterol-d6 is used as a standard to detect cholesterol concentration using chromatography technique. It is also used to measure the percentage of cholesterol absorption by intravenously administrating into experimental animals.
Cholesterol-d6 may be used as an internal standard in
- electrospray ionization tandem mass spectrometry (ESIMS/MS)
- gas chromatography–mass spectrometry (GC-MS)
- for spiking lipid extracts from Drosophila for liquid chromatography–mass spectrometry (LC-MS)
Biochem/physiol Actions
Cholesterol-d6 rich liposomes are used in understanding the kinetics of reverse cholesterol transport in lymphatic and aorta. It is used in the generation of stratum corneum (SC) lipid model systems for deuteration based neutron diffraction studies. Use of Cholesterol-d6 as a diet supplement has enabled the understanding cholesterol metabolism in the blood brain barrier.
Packaging
5 mL Amber Glass Screw Cap Vial (700172P-10mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
The tumor suppressor TERE1 (UBIAD1) prenyltransferase regulates the elevated cholesterol phenotype in castration resistant prostate cancer by controlling a program of ligand dependent SXR target genes
Testing, 4(7), 1075-1075 (2013)
Effects of a disrupted blood-brain barrier on cholesterol homeostasis in the brain
The Journal of Biological Chemistry, 289(34), 23712-23722 (2014)
Central leptin regulates total ceramide content and sterol regulatory element binding protein-1C proteolytic maturation in rat white adipose tissue
Endocrinology, 150(1), 169-178 (2008)
Biochemical membrane lipidomics during Drosophila development
Developmental Cell, 24(1), 98-111 (2013)
Cholesterol and Other Lipid Metabolism
Stable Isotope Characterization of TICs/TIMs: Analytical Progress Report. No. LLNL-TR-413939. Lawrence Livermore National Laboratory (LLNL), Livermore, CA, 2009., 157-157 (2003)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service