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T85308

Sigma-Aldrich

Tris(2-chloroethyl)amine hydrochloride

98%

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About This Item

Linear Formula:
(ClCH2CH2)3N·HCl
CAS Number:
Molecular Weight:
240.99
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

Assay

98%

mp

127-130 °C (lit.)

SMILES string

Cl.ClCCN(CCCl)CCCl

InChI

1S/C6H12Cl3N.ClH/c7-1-4-10(5-2-8)6-3-9;/h1-6H2;1H

InChI key

VEAUDLLZYJVHRI-UHFFFAOYSA-N

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 2 Oral - Carc. 2 - Skin Corr. 1B

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Trichloromethyl ketones as synthetically versatile donors: application in direct catalytic mannich-type reactions and the stereoselective synthesis of azetidines.
Hiroyuki Morimoto et al.
Angewandte Chemie (International ed. in English), 45(19), 3146-3150 (2006-04-06)
N I Riabchenko et al.
Radiobiologiia, 31(1), 22-26 (1991-01-01)
Regularities of chromatin degradation in thymocytes and LS/BL tumor cells have been investigated. It has been shown that the rate of DNA degradation by Ca/Mg-dependent endonuclease in LS/BL tumor cells is 25 times lower than that in thymocytes, and radiation
L Szinicz et al.
Arzneimittel-Forschung, 31(10), 1713-1717 (1981-01-01)
The effect of tris-(2-chloroethyl)-amine (HN-3) on RNA and DNA was investigated spectrophotometrically. The shift in the absorbance spectrum caused by the addition of HN-3 was used to test a variety of compounds for their ability to inhibit RNA alkylation. The
T Hiratsuka
Biochemistry, 27(11), 4110-4114 (1988-05-31)
The chemotherapeutic alkylating reagent tris(2-chloroethyl)amine (TCEA) was used as a trifunctional cross-linking reagent with a cross-linking span of 5 A for myosin subfragment 1 (S-1). When S-1 was incubated with TCEA, all three domains of 20, 26, and 50 kDa
D B Wildenauer et al.
Biochimica et biophysica acta, 603(1), 101-116 (1980-12-02)
The influence of tris(2-chloroethyl)amine on shape changes of human erythrocytes and ghosts was studied in vitro and correlated with alterations in the molecular structure of the membrane. (1) Reaction with 1--2 mM tris(2-chloroethyl)amine, a concentration which caused polymerisation of spectrin

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