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H6773

Sigma-Aldrich

Etidronic acid

60% aqueous solution

Synonym(s):

1-Hydroxyethane-1,1,-diphosphonic acid, 1-Hydroxyethylidenediphosphonic acid, HDEPA, OEDFK

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About This Item

Linear Formula:
CH3C(OH)[PO(OH)2]2
CAS Number:
Molecular Weight:
206.03
Beilstein:
1789291
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

suitability

suitable for photographic applications

SMILES string

CC(O)(P(O)(O)=O)P(O)(O)=O

InChI

1S/C2H8O7P2/c1-2(3,10(4,5)6)11(7,8)9/h3H,1H3,(H2,4,5,6)(H2,7,8,9)

InChI key

DBVJJBKOTRCVKF-UHFFFAOYSA-N

Application

Etidronic acid (HEBP) can be employed as a catalyst for the synthesis of:
  • 5-Nitro-3,4-dihydropyrimidin-2(1H)-ones through the reaction between 1-(2-hydroxyphenyl)-2-nitroethanone, aryl aldehydes and urea via one-pot cyclo condensation reaction.
  • Thiiranes from epoxides and ammonium thiocyanate.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Xiao-Xiong Wang et al.
Water research, 186, 116333-116333 (2020-08-29)
The effects of phosphonates, the heavily-used antiscalants in reverse osmosis systems, on microalgae are controversial, although they are harmless to most aquatic organisms. Herein, we assessed the inhibitory effects of etidronic acid (HEDP) and diethylenetriamine penta(methylene phosphonic acid) (DTPMP) on
Om Alkhir Alshanta et al.
Antibiotics (Basel, Switzerland), 9(9) (2020-09-26)
Endodontic infections are often interkingdom biofilms, though current clinical management rarely considers this phenomenon. This study aimed to evaluate new and standard endodontic antimicrobial regimens against simple and complex Candida albicans and Enterococcus faecalis mono- and dual-species biofilms. C. albicans
Etidronic acid: a new and efficient catalyst for the synthesis of novel 5-nitro-3, 4-dihydropyrimidin-2 (1H)-ones
Savant MM, et al.
Catalysis Letters, 132(1-2), 281-284 (2009)
Ping Yin et al.
Bioresource technology, 128, 36-43 (2012-12-01)
Novel biomass-based adsorbents organophosphonic acid functionalized spent buckwheat hulls (OPA-BH) with 60 mesh were successfully employed to adsorb Au(III) ions from simulated wastewater. The adsorption kinetics and isotherms both in unary ion system and in ternary ions system were investigated
Siyoung Kim et al.
European journal of pharmacology, 699(1-3), 14-22 (2012-12-04)
Nitrogen-containing bisphosphonates (NBPs) have greater anti-bone-resorptive effects than non-nitrogen-containing bisphosphonates (non-NBPs). Hence, NBPs are the current first-choice drug for osteoporosis. However, NBPs carry a risk of osteonecrosis of jaws. Some animal and human studies suggest that non-NBPs may have anti-bone-resorptive

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