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H45132

Sigma-Aldrich

5-Hydroxy-Nω-methyltryptamine oxalate

99%

Synonym(s):

3-(2-Methylaminoethyl)indol-5-ol oxalate, N-Methylserotonin oxalate

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About This Item

Empirical Formula (Hill Notation):
C13H16N2O5
CAS Number:
1975-81-1
Molecular Weight:
280.28
MDL number:
MFCD00013159
UNSPSC Code:
12352100
PubChem Substance ID:
24895517
NACRES:
NA.22

Quality Level

100

Assay

99%

mp

161-162 °C (dec.) (lit.)

SMILES string

OC(=O)C(O)=O.CNCCc1c[nH]c2ccc(O)cc12

InChI

1S/C11H14N2O.C2H2O4/c1-12-5-4-8-7-13-11-3-2-9(14)6-10(8)11;3-1(4)2(5)6/h2-3,6-7,12-14H,4-5H2,1H3;(H,3,4)(H,5,6)

InChI key

DYOZWAJOUTVNAF-UHFFFAOYSA-N

Related Categories

Application

  • reactant for preparation of 5-HT receptor agonists

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Albrecht Pfäfflin et al.
Annals of clinical biochemistry, 46(Pt 2), 146-148 (2009-01-20)
Serotonin is frequently analysed by high-performance liquid chromatography (HPLC) with electrochemical detection. However, the accuracy of these methods may be affected by the presence of certain drugs. We describe for the first time the interference of paracetamol in therapeutic dosages
Sharla L Powell et al.
Journal of agricultural and food chemistry, 56(24), 11718-11726 (2008-12-04)
Cimicifuga racemosa (L.) Nutt. (syn. Actaea racemosa L., black cohosh) is used to relieve menopausal hot flashes, although clinical studies have provided conflicting data, and the active constituent(s) and mechanism(s) of action remain unknown. Because serotonergic receptors and transporters are
D Alberghina et al.
Research in veterinary science, 90(3), 392-395 (2010-07-17)
To evaluate the changes in plasma and platelet serotonin (5-HT) as markers of the serotoninergic system in equines, 5-HT content was measured by high performance liquid chromatography (HPLC) in deproteinized plasma obtained from peripheral blood samples of 12 clinically healthy
A R Johnston et al.
Experimental brain research, 93(2), 293-298 (1993-01-01)
The effects of 5-hydroxytryptamine (5-HT) and related compounds on the discharge rate of tonically active medial vestibular nucleus (MVN) neurones were studied in an in vitro slice preparation of the dorsal brainstem of the rat. The majority (87 of 107
G L Laekeman et al.
Agents and actions, 16(5), 443-445 (1985-07-01)
Pharmacological effects of 5-hydroxykynuramine (5-HK) were investigated in chicken whole blood. It was shown that 5-HK had a time-depending inhibiting activity on platelet aggregation induced by 5-hydroxytryptamine (5-HT). Experiments were carried out in order to determine whether the inhibitory effect
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