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914487

Sigma-Aldrich

2-(Diphenylphosphanyl)benzamide

≥95%

Synonym(s):

2-(Diphenylphosphino)-benzamide, DPBM, Phosphine for Staundinger reduction

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About This Item

Empirical Formula (Hill Notation):
C19H16NOP
CAS Number:
Molecular Weight:
305.31
UNSPSC Code:
12352200
NACRES:
NA.22

Quality Level

Assay

≥95%

form

powder

storage temp.

−20°C

General description

It is recommended to make fresh stock stolutions prior to each use.

Application

2-(Diphenylphosphanyl)benzamide (DPBM) is a phosphine useful in the Staudinger reduction in chemical biology and medicinal chemistry. Recently, DPBM was demonstrated to faciliate the reactivation of CRISPR/Cas9 functions by removing azidomethylnicotinyl (AMN) groups used to masked gRNA and inhibit CRISPR systems. AMN groups were originally added with the use of RNA probe NAI-N3 (cat# 913812).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


Certificates of Analysis (COA)

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