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440752

Sigma-Aldrich

Polycaprolactone

average Mw ~14,000, average Mn ~10,000 by GPC

Synonym(s):

2-Oxepanone homopolymer, 6-Caprolactone polymer

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About This Item

Linear Formula:
(C6H10O2)n
UNSPSC Code:
12162002
NACRES:
NA.23

form

flakes or chunk(s)

mol wt

average Mn ~10,000 by GPC
average Mw ~14,000

viscosity

400-1000 mPa.s, 50 wt. % in xylene

mp

60 °C (lit.)

transition temp

Tg −60 °C

density

1.146 g/mL at 25 °C

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General description

Polycaprolactone is a α,ω-dihydroxy functional polymer.

Application

Polycaprolactone may find use as an extrusion aid, die lubricant, mold release, pigment and filler dispersion aid and polyester segments in urethanes and block polyesters.

Features and Benefits

Biodegradable polymer
Non-toxic, biodegradable in soil, broad miscibility, mechanical compatibility with many polymers and good adhesion to a broad spectrum of substrates.

Physical form

α,ω-dihydroxy functional polymer.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

>230.0 °F

Flash Point(C)

> 110 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sigma-Aldrich

38534

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The Journal of physiology, 597(20), 5063-5077 (2019-09-05)
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Poly(ϵ-caprolactone) (PCL), a biodegradable and biocompatible polymer, is useful to encapsulate a wide range of drugs making it an interesting material for the preparation of carriers with potential applications in therapeutics. The design and development of those carriers to modulate
André O'Reilly Beringhs et al.
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Contrast-enhanced X-ray computed tomography plays an important role in cancer imaging and disease progression monitoring. Imaging using radiopaque nanoparticle platforms can provide insights on the likelihood of nanoparticle accumulation and can enable image-guided therapies. Perfluorooctyl bromide (PFOB)-loaded nanocapsules designed for
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Galactosylated chitosan-polycaprolactone (Gal-CH-PCL) copolymers with a galactosylation degree of around 10% and varied PCL percentages less than 40 wt% were synthesized and used to produce nanoparticles for delivering curcumin. Some nanoparticles with encapsulation efficiency of 70% or higher and sizes
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