All Photos(1)
About This Item
Linear Formula:
BrCH2CH2OSi(CH3)2C(CH3)3
CAS Number:
Molecular Weight:
239.23
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
99%
form
liquid
contains
Na2CO3 as stabilizer
refractive index
n20/D 1.444 (lit.)
bp
70-75 °C/2.5 mmHg (lit.)
density
1.115 g/mL at 25 °C (lit.)
functional group
bromo
storage temp.
2-8°C
SMILES string
CC(C)(C)[Si](C)(C)OCCBr
InChI
1S/C8H19BrOSi/c1-8(2,3)11(4,5)10-7-6-9/h6-7H2,1-5H3
InChI key
JBKINHFZTVLNEM-UHFFFAOYSA-N
General description
(2-Bromoethoxy)-tert-butyldimethylsilane is a silane derivative.
Application
(2-Bromoethoxy)-tert-butyldimethylsilane was used in the synthesis of 4-(3-hydroxypropyl)-4′-methyl-2,2′-bipyridine.
It may be used as a reagent for the selective N-alkylation of 5-piperazin-1-yl-1H-indole and (1H-indol-2-yl)-piperazin-1-yl-methanone and also in the synthesis of 2-[3-[(3,4,5-trimethoxyphenyl)thio]-1H-indol-5-yloxy]ethanol.
It may be used as a reagent for the selective N-alkylation of 5-piperazin-1-yl-1H-indole and (1H-indol-2-yl)-piperazin-1-yl-methanone and also in the synthesis of 2-[3-[(3,4,5-trimethoxyphenyl)thio]-1H-indol-5-yloxy]ethanol.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
163.4 °F - closed cup
Flash Point(C)
73 °C - closed cup
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Hansen, Joshua; et al.
Tetrahedron Letters, 47(1), 69-72 (2005)
Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studies.
La Regina G, et al.
Journal of Medicinal Chemistry, 50(12), 2865-2874 (2007)
Cyril Bressy et al.
Journal of the American Chemical Society, 127(38), 13148-13149 (2005-09-22)
A norbornene-mediated palladium-catalyzed tandem alkylation/C-H functionalization sequence is described, in which an alkyl-aryl bond and a heteroaryl-aryl bond are formed in one pot. A variety of highly substituted six- and seven-membered ring annulated indoles were synthesized in good yields from
Tetrahedron Letters, 47, 69-69 (2006)
Mark Johnson et al.
Journal of medicinal chemistry, 55(12), 5826-5840 (2012-05-31)
In our effort to develop multifunctional drugs against Parkinson's disease, a structure-activity-relationship study was carried out based on our hybrid molecular template targeting D2/D3 receptors. Competitive binding with [(3)H]spiroperidol was used to evaluate affinity (K(i)) of test compounds. Functional activity
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service