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308633

Sigma-Aldrich

2-Hydroxyethyl cellulose

average Mw ~380,000

Synonym(s):

HEC

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About This Item

CAS Number:
9004-62-0
MDL number:
MFCD00072770
UNSPSC Code:
12162002
NACRES:
NA.23

description

Viscosity:300 - 400 cps, c = 2%; Water at 25° C

form

powder

autoignition temp.

725 °F

mol wt

average Mw ~380,000

extent of labeling

1.0 mol per mol cellulose (D.S.)
2.0 mol per mol cellulose (M.S.)

mp

288-290 °C (dec.)

density

0.6 g/mL at 25 °C (lit.)

InChI

1S/C29H52O21/c1-10-15(34)16(35)24(13(8-33)45-10)49-28-20(39)18(37)25(50-29-26(43-5-4-30)21(40)23(42-3)12(7-32)47-29)14(48-28)9-44-27-19(38)17(36)22(41-2)11(6-31)46-27/h10-40H,4-9H2,1-3H3

InChI key

CWSZBVAUYPTXTG-UHFFFAOYSA-N

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General description

2-Hydroxyethyl cellulose (HEC) is a water soluble biopolymer that is majorly used as a thickener and an adhesive. It has water retention which also includes good film forming ability for protective covering.
Non-ionic water soluble polymer. Aqueous solutions are pseudoplastic. Readily disperses without lumping.

Application

Thickener, protective colloid, binder, stabilizer and suspending agent.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Chemical modification of cellulose extracted from sugarcane bagasse: Preparation of hydroxyethyl cellulose
Abdel-Halim ES
Arabian Journal of Chemistry, 7(3), 362-371 (2014)
Distribution of substituents in O-(2-hydroxyethyl) cellulose
Lindberg B, et al.
Carbohydrate Research, 170(2), 207-214 (1987)
Prem N Gupta et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 46(5), 315-322 (2012-03-01)
Mucosally-administered vaccine strategies are widely investigated as a promising means of preventing HIV infection. This study describes the development of liposomal gel formulations, and novel lyophilised variants, comprising HIV-1 envelope glycoprotein, CN54gp140, encapsulated within neutral, positively charged or negatively charged
Maoqiang Xue et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 912, 1-7 (2013-01-08)
Microporous anodic aluminum oxide (AAO) membranes were modified by 3-glycidoxypropyltrimethoxysilane to produce terminal epoxy groups. These were used to covalently link hydroxyethyl celluloses (HEC) to amplify reactive groups of AAO membrane. The hydroxyl groups of HEC-AAO composite membrane were further
Liangzhu Li et al.
PloS one, 7(5), e37381-e37381 (2012-05-23)
Sifuvirtide is a proven effective HIV-1 entry inhibitor and its safety profile has been established for systemic administration. The present study evaluated the potential of sifuvirtide formulated in a universal gel for topical use as a microbicide candidate for preventing
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