Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

147443

Sigma-Aldrich

3-Chloropropionyl chloride

technical grade

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
ClCH2CH2COCl
CAS Number:
625-36-5
Molecular Weight:
126.97
Beilstein:
635814
EC Number:
210-890-4
MDL number:
MFCD00000747
UNSPSC Code:
12352100
PubChem Substance ID:
24848553
NACRES:
NA.22

grade

technical grade

Quality Level

100

form

liquid

refractive index

n20/D 1.457 (lit.)

bp

143-145 °C (lit.)

density

1.33 g/mL at 25 °C (lit.)

functional group

acyl chloride
chloro

SMILES string

ClCCC(Cl)=O

InChI

1S/C3H4Cl2O/c4-2-1-3(5)6/h1-2H2

InChI key

INUNLMUAPJVRME-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

3-Chloropropionyl chloride was used to modify hydrophilic and macroporous polymer resins composed of glycerylmethacrylate, styrene and divinylbenzene. It was used in the synthesis of diethylaminopropionamido-hydroxy-anthraquinones, which are potential anticancer agents.

Pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

Signal Word

Danger

Hazard Statements

H290,H302,H314,H330

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1A

Supplementary Hazards

EUH014

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

Flash Point(F)

158.9 °F - closed cup

Flash Point(C)

70.5 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
STBG5236V
STBF4616V
STBF4118V
STBF3610V
STBF1361V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 2

1 of 2

2-Bromopropionyl bromide 97%

Sigma-Aldrich

249785

2-Bromopropionyl bromide

N-Bromosuccinimide ReagentPlus®, 99%

Sigma-Aldrich

B81255

N-Bromosuccinimide

M Hasegawa et al.
Biotechnology and bioengineering, 36(3), 219-223 (1990-07-01)
Hydrophilic and macroporous polymer resins composed of glycerylmethacrylate, styrene, and divinylbenzene were quite easily modified with isothiocyanate groups using a Friedel-Crafts reaction with 3-chloropropionyl chloride and subsequent nucleophilic reaction with KSCN. Alkaline phosphatase and trypsin could be covalently bound to
C Antonello et al.
Archiv der Pharmazie, 322(9), 541-544 (1989-09-01)
A number of new 9,10-anthracenediones were obtained, bearing one or two hydroxyl groups and one positively charged side chain at different positions of the aromatic ring system (compounds 1-5 in Chart 1). These derivatives resemble the anticancer agents mitoxantrone and

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service