High-Purity Solvents: UHPLC-MS, LC-MS, & HPLC Instrumental Analyses

We are committed to providing our customers with the widest selection of high-purity solvents, specifically designed to deliver ultimate performance in UHPLC-MS, LC-MS, and HPLC Instrumental Analysis. In agreement with our commitment, we offer solvents under two premium brands: LiChrosolv^® solvents and OmniSolv^® solvents (only in the US and Canada) under the Supelco^® portfolio for regulated/accredited application fields and SigmaAldrich^® portfolio for research fields. Our large portfolios of analytical solvents allow for reliable, accurate, and reproducible results without demanding costly purification and repeated analyses. Also, our latest advancement in purification technology reaches a new quality milestone in the category of high-purity solvents, thereby enabling accurate and reproducible results.

Portfolio Brand	Grades	Applications	Packaging	Features
Supelco® LiChrosolv® & OmniSolv® (NA) SigmaAldrich®	HPLC Solvents	HPLC-UV	Amber bottles Aluminum bottles Recyclers	Microfiltered (0.2 μm) Extensive QC testing ensures lot-to-lot consistency
Supelco® LiChrosolv®, & OmniSolv® (NA) SigmaAldrich®	HPLC Isocratic Solvents	HPLC Isocratic elution	Amber bottles Aluminum bottles Recyclers	Microfiltered (0.2 μm) Low UV profile LC Isocratic suitible; tested for use in LC-UV applications Lot-to-lot consistency
Supelco® LiChrosolv®, & OmniSolv® (NA) SigmaAldrich®	HPLC Gradient Solvents	HPLC Gradient elution	Amber bottles Aluminum bottles Recyclers	Microfiltered (0.2 μm) Low UV profile Low impurity gradient LC baseline No interferences Lot-to-lot consistency
Supelco® & OmniSolv® (NA) SigmaAldrich®	HPLC Plus Solvents	HPLC gradient, UV and GC residue analysis	Amber bottles Recyclers	Microfiltered (0.2 μm) Low UV profile for use near a solvent’ UV cut off High-purity & low gradient baseline drift specs meets demanding LC-UV and some LC-MS applications Suitability tested for GC analysis Low levels of particles and non-volatile impurities
Supelco® LiChrosolv®, & OmniSolv® NA)	LC-MS Solvents	LC-MS/MS	Amber bottles Recyclers	Microfiltered (0.2 μm) Clean UV Impurity profile maximizes sensitivity near UV cut off LC-MS suitability Low particulates levels and non-volatile impurities increases the longevity of columns and systems. Low levels of alkali metal impurities Lot-to-lot consistency
Supelco® LiChrosolv®, SigmaAldrich®	UHPLC-MS Solvents	UHPLC-MS/MS &UHPLC-UV	Borosilicate bottles	Microfiltered (0.2 μm)-No increase in back pressure due to the solvent Extremely low detection limits using any detection mode Suitability tested by UHPLC-UV/MS & UHPLC-MS TOF with the tightest specification for both positive & negative MS modes. High-purity for extremely low detection limits under any detection mode Extremely low baseline with a minimum of impurity peaks e.g. phthalates and PEG Minimum MS-adduct formation caused by leakage of alkali ions over time Lot-to-lot reproducibility