Fusaric Acid immunotoxicity and MAPK activation in normal peripheral blood mononuclear cells and Thp-1 cells.

Fusaric Acid immunotoxicity and MAPK activation in normal peripheral blood mononuclear cells and Thp-1 cells.

Scientific reports (2017-06-10)

Shanel Dhani, Savania Nagiah, Dhaneshree B Naidoo, Anil A Chuturgoon

摘要

Fusaric acid (FA), a food-borne mycotoxin, is a potent divalent metal chelator. The human immune system is complex and susceptible to environmental insult however, the immunotoxity of FA remains unknown. We investigated the immunotoxicity of FA on human peripheral blood mononuclear cells (PBMCs) and Thp-1 cells. FA was cytotoxic to PBMCs (IC

材料

货号

品牌

产品描述

A3854

Sigma-Aldrich

抗-β-肌动蛋白−过氧化物酶抗体，小鼠单克隆小鼠抗, clone AC-15, purified from hybridoma cell culture

M8177

Sigma-Aldrich

Anti-p38 MAP Kinase, Activated (Diphosphorylated p38) antibody, Mouse monoclonal, clone P38-TY, purified from hybridoma cell culture, buffered aqueous solution