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Merck

Novel conserved assembly factor of the bacterial flagellum.

Journal of bacteriology (2006-08-29)
Björn Titz, Seesandra V Rajagopala, Claudia Ester, Roman Häuser, Peter Uetz
摘要

TP0658 (FliW) and its orthologs, conserved proteins of unknown function in Treponema pallidum and other species, interact with a C-terminal region of flagellin (FlaB1-3 in T. pallidum; FliC in most other species). Mutants of orthologs in Bacillus subtilis and Campylobacter jejuni (yviF, CJ1075) showed strongly reduced motility. TP0658 stabilizes flagellin in a way similar to FliS, suggesting that TP0658 is a conserved assembly factor for the bacterial flagellum.