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Merck

Drug evaluation: OPT-80, a narrow-spectrum macrocyclic antibiotic.

Current opinion in investigational drugs (London, England : 2000) (2007-03-03)
Alan P Johnson
摘要

Optimer Pharmaceuticals Inc, in collaboration with Par Pharmaceutical Companies Inc, is developing OPT-80, a narrow-spectrum macrocyclic antibiotic secreted by the actinomycete Dactylosporangium aurantiacum, for the potential treatment of Clostridium difficile-associated diarrhea (CDAD) and vancomycin-resistant Enterococcus infection. A phase IIb/III clinical trial of OPT-80 in patients with CDAD is underway.

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Sigma-Aldrich
Fidaxomicin, ≥95% (HPLC)