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Synthesis of YF3: Yb, Er upconverting nanofluorophores using chitosan and their cytotoxicity in MCF-7 cells.

Synthesis of YF3: Yb, Er upconverting nanofluorophores using chitosan and their cytotoxicity in MCF-7 cells.

International journal of biological macromolecules (2014-12-03)

Sethuraman Gayathri, Oriparambil Sivaraman Nirmal Ghosh, Annamraju Kasi Viswanath, P Sudhakara, M Jeevan Kumar Reddy, A M Shanmugharaj

摘要

In this work, we described one pot hydrothermal synthesis of surface modified water soluble YF3: Yb, Er upconverting nanofluorophores (UCNFs) using natural biopolymer chitosan. The obtained nanocrystals have undergone X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), high resolution transmission electron microscopy (HRTEM) and photoluminescence (PL) studies. The nanoparticles possess uniform particle size distribution with average size about 27 nm. The cytotoxicity results revealed that the chitosan capped nanoparticles exhibit excellent biocompatibility in human breast cancer cells. In conclusion, the water soluble chitosan capped YF3: Yb, Er nanoparticles could be used as a potential candidate in bio-imaging and therapeutic applications.

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纯乙醇, 200 proof, anhydrous, ≥99.5%

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氯化钇 (III), anhydrous, powder, 99.99% trace metals basis

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10% (v/v) 乙醇标准品, 10 % (v/v) in H₂O, analytical standard

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氯化钇 (III), AnhydroBeads^™, −10 mesh, 99.99% trace metals basis

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酒精, ≥99.5%, suitable for fluorescence

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镱, lump, 50g, max. size 25mm, 99.9%

镱, rod, 100mm, diameter 6.35mm, cast, 99%

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