- TRPML and lysosomal function.
TRPML and lysosomal function.
Biochimica et biophysica acta (2007-02-20)
David A Zeevi, Ayala Frumkin, Gideon Bach
PMID17306511
摘要
Mucolipin 1 (MLN1), also known as TRPML1, is a member of the mucolipin family. The mucolipins are the only lysosomal proteins within the TRP superfamily. Mutations in the gene coding for TRPML1 result in a lysosomal storage disorder (LSD). This review summarizes the current knowledge related to this protein and the rest of the mucolipin family.