Fungicide chinomethionate as a new family of photoinducible DNA-cleaving agents.

Fungicide chinomethionate as a new family of photoinducible DNA-cleaving agents.

Bioorganic & medicinal chemistry letters (2003-09-25)

Jianying Qi, Tianhu Li, Albert S C Chan

摘要

It is demonstrated for the first time in this report that chinomethionate is capable of causing efficient DNA cleavage under mild irradiation conditions, a fungicide molecule that processes the simple group of 1,3-dithio-2-one as its reactive functionality.