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Merck
  • Synthesis and in vitro anthelmintic activity against Nippostrongylus brasiliensis of new 2-amino-4-hydroxy-delta-valerolactam derivatives.

Synthesis and in vitro anthelmintic activity against Nippostrongylus brasiliensis of new 2-amino-4-hydroxy-delta-valerolactam derivatives.

Farmaco (Societa chimica italiana : 1989) (1998-05-15)
S Gordon, L Costa, M Incerti, E Manta, J Saldaña, L Domínguez, R Mariezcurrena, L Suescun
摘要

The synthesis of a series of 2-amino-4-hydroxy-delta-valerolactam derivatives is described (compounds 4 to 10). These compounds showed a high anthelmintic in vitro activity against the Nippostrongylus brasiliensis model.

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Sigma-Aldrich
2-氮己环酮, 98%