Investigation of the impurities found in methamphetamine synthesised from pseudoephedrine by reduction with hydriodic acid and red phosphorus.

Investigation of the impurities found in methamphetamine synthesised from pseudoephedrine by reduction with hydriodic acid and red phosphorus.

Forensic science international (1995-12-18)

K L Windahl, M J McTigue, J R Pearson, S J Pratt, J E Rowe, E M Sear

摘要

The synthesis of methamphetamine from pseudoephedrine via the reduction with hydriodic acid and red phosphorus was studied and the impurities which were generated, along with the methamphetamine, were investigated. Some of the impurities found have been reported previously, while the diastereoisomers of N-methyl-N-(alpha- methylphenethyl)amino-1-phenyl-2-propanone and the cis-cinnamoyl derivative of methamphetamine are reported here for the first time. Further work on the sequence of reactions occurring in this reduction is also reported.

材料

货号

品牌

产品描述

210021

Sigma-Aldrich

氢碘酸, 57 wt. % in H₂O, distilled, stabilized, 99.95%

398098

Sigma-Aldrich

氢碘酸, contains no stabilizer, ACS reagent, 55%

210013

Sigma-Aldrich

氢碘酸, contains no stabilizer, distilled, 57 wt. % in H₂O, 99.99% trace metals basis

248649

Sigma-Aldrich

氢碘酸, contains ≤1.5% hypophosphorous acid as stabilizer, ACS reagent, ≥47.0%

752851

Sigma-Aldrich

氢碘酸, 57 wt. %, distilled, 99.999% trace metals basis