- [Experimental models of lysosomal phase reactivity in blood leukocytes exposed to low doses of potassium cyanide].
[Experimental models of lysosomal phase reactivity in blood leukocytes exposed to low doses of potassium cyanide].
Meditsina truda i promyshlennaia ekologiia (2013-06-22)
M V Dolgushin, G D Khomuev
PMID23785827
摘要
Cytochemical analysis of acid phosphatase was used to evaluate lysosomal membranes stability under oral intake of potassium cyanide by rats over one month in daily doses of 1.30 mg/kg (1/10 LD50) and 0.65 mg/kg (1/20 LD50). The authors demonstrated phase-related dose-dependent changes in the lysosomal state, and the main response feature was associated with functional activation that usually followed the membrane alteration.