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[Research of bornrol promote drugs through blood-brain barrier].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (2012-07-17)
Xuxiao Lv, Mingjiang Sun, Fengzhi Sun
摘要

Malignant tumor, epilepsy, dementia, cerebral ischemia and other brain diseases have very high rates of disability and mortality. Currently, many drugs are developed to treat such diseases and the effect is obviously. But they can not achieve the purpose to control these diseases because many of the drugs can not pass through the blood-brain barrier (BBB). Therefore, the treatment is not good. Borneol as the represent of the aromatic resuscitation medicine, it has strong fat-soluble active ingredients, small molecular weight, volatile and through the BBB quickly. It can also promote other therapeutic drugs through the BBB. It has two-ways regulations on BBB permeability and the damage of brain tissue is small, this have important theoretical significances and application values.

材料
货号
品牌
产品描述

Sigma-Aldrich
(−)-右旋龙脑, predominantly endo, 97%
Sigma-Aldrich
(+)-冰片, 97%
Sigma-Aldrich
异冰片, 95%
Supelco
2-茨醇, analytical standard
Supelco
(+)-冰片, analytical standard