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Hypoxylonols C-F, benzo[j]fluoranthenes from Hypoxylon truncatum.

Journal of natural products (2011-12-14)
Miyuki Fukai, Mariko Tsukada, Kazuhiko Miki, Toshihiro Suzuki, Takashi Sugita, Kaoru Kinoshita, Kunio Takahashi, Motoo Shiro, Kiyotaka Koyama
摘要

Four novel benzo[j]fluoranthene derivatives, hypoxylonols C (3), D (4), E (5), and F (6), have been isolated from the mushroom Hypoxylon truncatum, together with two known benzo[j]fluoranthene derivatives, hypoxylonols A (1) and B (2). The structures were established by analysis of NMR spectroscopic data and X-ray diffraction data. Compounds 4 and 5 showed antiproliferative activity against HUVECs (human umbilical vein endothelial cells) and HUAECs (human umbilical artery endothelial cells).

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Supelco
苯并[j]荧蒽 溶液, certified reference material, 2000 μg/mL in dichloromethane