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Merck

WHSC1

Wolf-Hirschhorn syndrome candidate 1

别名:
MMSET, NSD2, REIIBP, TRX5, WHS
物种:
UniProtKB ID:
基因ID:
  • Human(7468) Summary: This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. [provided by RefSeq, Jul 2008]
  • Mouse(107823) Wolf-Hirschhorn syndrome candidate 1 (human)
  • Rat(680537) Wolf-Hirschhorn syndrome candidate 1
  • Horse(100051090) Wolf-Hirschhorn syndrome candidate 1
  • domestic guinea pig(100713660) Wolf-Hirschhorn syndrome candidate 1
  • cow(540769) Wolf-Hirschhorn syndrome candidate 1
  • domestic cat(101083169) Wolf-Hirschhorn syndrome candidate 1
  • naked mole-rat(101709487) Wolf-Hirschhorn syndrome candidate 1
  • chicken(422897) Wolf-Hirschhorn syndrome candidate 1
  • dog(479077) Wolf-Hirschhorn syndrome candidate 1
  • Zebrafish(100000709) Wolf-Hirschhorn syndrome candidate 1
  • sheep(101103648) Wolf-Hirschhorn syndrome candidate 1

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Antibodies

货号
说明
物种反应性
应用
WHSC1/NSD2抗体,克隆29D1, clone 29D1, from mouse,
物种反应性
human
应用
ChIP
immunoprecipitation (IP)

western blot
Anti-NSD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
单克隆抗-NSD2 小鼠抗, Prestige Antibodies® Powered by Atlas Antibodies, clone CL1063, purified immunoglobulin, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-NSD2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL1057, purified immunoglobulin, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-NSD2 Antibody, from rabbit, purified by affinity chromatography,
物种反应性
human
应用
immunohistochemistry
immunoprecipitation (IP)

western blot

Proteins

货号
说明
物种
NSD2 (782-end)/ReBPII Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human WHSC1,
物种
human