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Merck

TRPV4

transient receptor potential cation channel, subfamily V, member 4

别名:
CMT2C, HMSN2C, OTRPC4, SMAL, SPSMA, SSQTL1, TRP12, VRL2, VROAC
物种:
UniProtKB ID:
基因ID:
  • Human(59341) Summary: This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
  • Mouse(63873) transient receptor potential cation channel, subfamily V, member 4
  • Rat(66026) transient receptor potential cation channel, subfamily V, member 4
  • naked mole-rat(101706710) transient receptor potential cation channel, subfamily V, member 4
  • domestic guinea pig(100724607) transient receptor potential cation channel, subfamily V, member 4
  • sheep(101113534) transient receptor potential cation channel, subfamily V, member 4
  • domestic cat(101084907) transient receptor potential cation channel, subfamily V, member 4
  • Horse(100066552) transient receptor potential cation channel, subfamily V, member 4
  • cow(540259) transient receptor potential cation channel, subfamily V, member 4
  • chicken(395427) transient receptor potential cation channel, subfamily V, member 4
  • dog(486308) transient receptor potential cation channel, subfamily V, member 4
  • Zebrafish(557850) transient receptor potential cation channel, subfamily V, member 4

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Small Molecule - Agonist

货号
说明
物种
二氢辣椒碱, from Capsicum sp., ≥85%,
物种
rat, human
N-香草基壬酰胺, ≥97%, powder,
物种
rat

Small Molecule - Antagonist

货号
说明
物种
辣椒平, ≥98% (HPLC), solid,
物种
human, rat
辣椒素, ≥95%, from Capsicum sp.,
物种
rat, human
辣椒素, natural,
物种
rat, human
辣椒素, from Capsicum sp., ≥50% (HPLC),
物种
rat, human
2,2′:5′,2′′:5′′,2′′′-四噻吩, 96%,
物种
human, rat, mouse

Antibodies

货号
说明
物种反应性
应用
Anti-TRPV4 Antibody, clone 1G10-L2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
canine, human, mouse, rat
应用
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
抗-Trpv4抗体,克隆1B2.6, clone 1B2.6, from mouse,
物种反应性
human, mouse
应用
immunocytochemistry
western blot
Anti-TRPV4 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
物种反应性
rat
应用
western blot
Anti-Transient Receptor Potential Vanilloid 4 Antibody, pain, Chemicon®, from rabbit,
物种反应性
rat
应用
western blot
抗-TRPV4 兔抗, affinity isolated antibody,
物种反应性
human, rabbit
应用
immunohistochemistry
western blot

Small Molecule - Inhibitor

货号
说明
物种
氨苯丁酯, United States Pharmacopeia (USP) Reference Standard,
物种
human
辣椒素, ≥95%, from Capsicum sp.,
物种
rat, human
辣椒素, natural,
物种
rat, human
辣椒素, from Capsicum sp., ≥50% (HPLC),
物种
rat, human
2,2′:5′,2′′:5′′,2′′′-四噻吩, 96%,
物种
human, rat, mouse

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
N-香草基壬酰胺, ≥97%, powder,
物种
rat
辣椒平, ≥98% (HPLC), solid,
物种
human, rat

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Trpv4,
物种
mouse
MISSION® esiRNA, targeting human TRPV4,
物种
human