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Merck

TRPV1

transient receptor potential cation channel, subfamily V, member 1

别名:
VR1
物种:
UniProtKB ID:
基因ID:
  • Human(7442) Summary: Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(193034) transient receptor potential cation channel, subfamily V, member 1
  • Rat(83810) transient receptor potential cation channel, subfamily V, member 1
  • domestic cat(101093406) transient receptor potential cation channel, subfamily V, member 1
  • chicken(395259) transient receptor potential cation channel, subfamily V, member 1
  • naked mole-rat(101720480) transient receptor potential cation channel, subfamily V, member 1
  • Domestic Rabbit(100008926) transient receptor potential cation channel, subfamily V, member 1
  • domestic cat(100303454) transient receptor potential cation channel, subfamily V, member 1
  • Zebrafish(561195) transient receptor potential cation channel, subfamily V, member 1
  • cow(539074) transient receptor potential cation channel, subfamily V, member 1
  • domestic guinea pig(100135466) transient receptor potential cation channel, subfamily V, member 1
  • Horse(100034158) transient receptor potential cation channel, subfamily V, member 1
  • sheep(101110158) transient receptor potential cation channel, subfamily V, member 1
  • dog(445457) transient receptor potential cation channel, subfamily V, member 1

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Small Molecule - Agonist

货号
说明
物种
二氢辣椒碱, from Capsicum sp., ≥85%,
物种
rat, human
N-香草基壬酰胺, ≥97%, powder,
物种
rat
油酰单乙醇胺, ~98% (TLC),
物种
human, mouse, rat

Small Molecule - Antagonist

货号
说明
物种
SB-366791, ≥98% (HPLC), powder,
物种
human
6-Iodonordihydrocapsaicin, ≥98% (HPLC), solid,
物种
human
辣椒平, ≥98% (HPLC), solid,
物种
human, rat
辣椒素, ≥95%, from Capsicum sp.,
物种
rat, human
辣椒素, natural,
物种
rat, human

Antibodies

货号
说明
物种反应性
应用
抗辣椒素受体抗体,CT, serum, Chemicon®,
物种反应性
rat
应用
immunohistochemistry
Anti-TRPV1 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
western blot
抗-TRPV1 兔抗, affinity isolated antibody,
物种反应性
human
应用
ELISA
western blot
单克隆抗-TRPV1 小鼠抗, clone 1F5, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Anti-TRPV1 Antibody, clone 1N19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey, mouse
应用
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

Small Molecule - Inhibitor

货号
说明
物种
Olvanil, powder,
物种
human
辣椒素, ≥95%, from Capsicum sp.,
物种
rat, human
对乙酰氨基酚, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
对乙酰氨基酚, United States Pharmacopeia (USP) Reference Standard,
物种
human
对乙酰氨基酚, BioXtra, ≥99.0%,
物种
human

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
N-香草基壬酰胺, ≥97%, powder,
物种
rat
辣椒平, ≥98% (HPLC), solid,
物种
human, rat

Small Molecule - Opener

货号
说明
物种
辣椒素, analytical standard,
物种
human
辣椒素, United States Pharmacopeia (USP) Reference Standard,
物种
human
辣椒碱, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
辣椒素, phyproof® Reference Substance,
物种
human
辣椒素, European Pharmacopoeia (EP) Reference Standard,
物种
human

Proteins

货号
说明
物种
Capsaicin Receptor Control Peptide for AB5889, ,
物种
rat

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human TRPV1,
物种
human
MISSION® esiRNA, targeting mouse Trpv1,
物种
mouse