跳转至内容
Merck

TP53

tumor protein p53

别名:
BCC7, LFS1, P53, TRP53
物种:
UniProtKB ID:
基因ID:
  • Human(7157) Summary: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]
  • Rat(24842) tumor protein p53
  • Domestic Rabbit(100009292) tumor protein p53
  • domestic guinea pig(100379269) tumor protein p53
  • sheep(443421) tumor protein p53
  • cow(281542) tumor protein p53
  • Zebrafish(30590) tumor protein p53
  • naked mole-rat(101701769) tumor protein p53
  • dog(403869) tumor protein p53
  • chicken(396200) tumor protein p53
  • Horse(100062044) tumor protein p53
  • domestic cat(493847) tumor protein p53

Custom & Knockdown Gene Products

Antibodies

产品编号
说明
物种反应性
应用
抗-p53(野生型)抗体,克隆PAb1620, clone Pab1620, from mouse,
物种反应性
human, mouse
应用
immunohistochemistry
western blot
Anti-p53 (Ab-6) (Pantropic) Mouse mAb (DO-1), liquid, clone DO-1, Calbiochem®,
物种反应性
feline, human
应用
p53(Ab-3)(突变型)小鼠单克隆抗体(PAb240), liquid, clone PAb240, Calbiochem®,
物种反应性
bovine, chicken, hamster, human, mouse, rat
应用
抗-P53(Ab-5)(野生型)小鼠mAb(PAb1620), liquid, clone PAb1620, Calbiochem®,
物种反应性
bovine, human, mouse, primate, rat
应用
Anti-p53 (pantropic) Antibody, clone DO-1, clone DO-1, from mouse,
物种反应性
human
应用
immunocytochemistry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot

Proteins

产品编号
说明
物种
p53 Protein, 10 µg, Full length, recombinant human p53. N-terminal c-Myc, 6His-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.,
物种
p53-GST (recombinant protein), ,
物种