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Merck

TNK2

tyrosine kinase, non-receptor, 2

别名:
ACK, ACK-1, ACK1, p21cdc42Hs
物种:
UniProtKB ID:
基因ID:
  • Human(10188) Summary: This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]
  • Mouse(51789) tyrosine kinase, non-receptor, 2
  • Rat(303882) tyrosine kinase, non-receptor, 2
  • naked mole-rat(101701156) tyrosine kinase, non-receptor, 2
  • sheep(101122917) tyrosine kinase, non-receptor, 2
  • cow(280710) tyrosine kinase, non-receptor, 2
  • domestic guinea pig(100715920) tyrosine kinase, non-receptor, 2
  • domestic cat(101098817) tyrosine kinase, non-receptor, 2
  • chicken(431014) tyrosine kinase, non-receptor, 2
  • dog(488025) tyrosine kinase, non-receptor, 2

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ELISA

货号
说明
物种
磷酸酪氨酸TNK2 /活化CDC42激酶1 ELISA试剂盒, ,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-phospho-ACK1 (Tyr284) Antibody, Upstate®, from rabbit,
物种反应性
human
应用
dot blot
inhibition assay

western blot
Anti-phospho-ACK1 (pTyr284) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse
应用
immunohistochemistry
western blot
Anti-TNK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-Phospho-TNK2-Y284 antibody produced in rabbit, ,
物种反应性
human
应用
western blot
Anti-phospho-ACK1 (pTyr284) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

immunohistochemistry

western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human TNK2,
物种
human
MISSION® esiRNA, targeting mouse Tnk2,
物种
mouse