跳转至内容
Merck

TNFSF15

tumor necrosis factor (ligand) superfamily, member 15

别名:
TL1, TL1A, VEGI, VEGI192A
物种:
UniProtKB ID:
基因ID:
  • Human(9966) Summary: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
  • Mouse(326623) tumor necrosis factor (ligand) superfamily, member 15
  • Rat(252878) tumor necrosis factor (ligand) superfamily, member 15
  • domestic cat(101099505) tumor necrosis factor (ligand) superfamily, member 15
  • chicken(417247) tumor necrosis factor (ligand) superfamily, member 15
  • naked mole-rat(101720658) tumor necrosis factor (ligand) superfamily, member 15
  • domestic guinea pig(100725797) tumor necrosis factor (ligand) superfamily, member 15
  • sheep(101102957) tumor necrosis factor (ligand) superfamily, member 15
  • dog(481688) tumor necrosis factor (ligand) superfamily, member 15
  • cow(514239) tumor necrosis factor (ligand) superfamily, member 15

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Anti-TNFSF15 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-TNFSF15 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-TNFSF15 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence

Proteins

货号
说明
物种
TL-1A human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human TNFSF15,
物种
human
MISSION® esiRNA, targeting mouse Tnfsf15,
物种
mouse