跳转至内容
Merck

TLR4

toll-like receptor 4

别名:
ARMD10, CD284, TLR-4, TOLL
物种:
UniProtKB ID:
基因ID:
  • Human(7099) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
  • Mouse(21898) toll-like receptor 4
  • Rat(29260) toll-like receptor 4
  • naked mole-rat(101715916) toll-like receptor 4
  • dog(403417) toll-like receptor 4
  • cow(281536) toll-like receptor 4
  • Horse(100066890) toll-like receptor 4
  • Domestic Rabbit(100009497) toll-like receptor 4
  • sheep(554263) toll-like receptor 4
  • Goat(100860955) toll-like receptor 4
  • domestic guinea pig(100724803) toll-like receptor 4
  • domestic cat(493698) toll-like receptor 4
  • chicken(417241) toll-like receptor 4

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

货号
说明
物种
人TLR-4 ELISA试剂盒, for cell culture supernatants, plasma, and serum samples,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-TLR4 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-TLR4 antibody produced in mouse, clone 3B6, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunohistochemistry

western blot
Anti-TLR4 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
抗-TLR4 兔抗, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunocytochemistry

immunofluorescence

immunohistochemistry

western blot
Anti-TLR4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human TLR4,
物种
human