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Merck

PRKCH

protein kinase C, eta

别名:
PKC-L, PKCL, PRKCL, nPKC-eta
物种:
UniProtKB ID:
基因ID:
  • Human(5583) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene. [provided by RefSeq, Jul 2008]
  • Mouse(18755) protein kinase C, eta
  • Rat(81749) protein kinase C, eta
  • Horse(100051560) protein kinase C, eta
  • domestic guinea pig(100736222) protein kinase C, eta
  • domestic cat(101082413) protein kinase C, eta
  • dog(490722) protein kinase C, eta
  • Domestic Rabbit(100344184) protein kinase C, eta
  • sheep(101105574) protein kinase C, eta
  • cow(518542) protein kinase C, eta
  • chicken(423518) protein kinase C, eta
  • naked mole-rat(101716769) protein kinase C, eta

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Small Molecule - Agonist

货号
说明
物种
油酸, ≥99% (GC),
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-phospho-PKCη (Thr655) Antibody, Upstate®, from rabbit,
物种反应性
human
应用
western blot
Anti-PRKCH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-PRKCH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-PRKCH antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-phospho-PKC-pan (pThr497) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Inhibitor

货号
说明
物种
呫吨酮, 97%,
物种
mouse
H-7 dihydrochloride, ≥98% (HPLC),
物种
human
他莫昔芬 柠檬酸盐, ≥99%,
物种
human
油酸, ≥99% (GC),
物种
human
UCN-01, ≥97% (HPLC), powder,
物种
human

Proteins

货号
说明
物种
PKC η Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant amino acids 2-end, of human PKC eta. For use in Kinase Assays.,
物种
human
PKCη, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Prkch,
物种
mouse
MISSION® esiRNA, targeting human PRKCH,
物种
human