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Merck

PPP1CA

protein phosphatase 1, catalytic subunit, alpha isozyme

别名:
PP-1A, PP1A, PP1alpha, PPP1A
物种:
UniProtKB ID:
基因ID:
  • Human(5499) Summary: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(19045) protein phosphatase 1, catalytic subunit, alpha isoform
  • Rat(24668) protein phosphatase 1, catalytic subunit, alpha isozyme
  • domestic guinea pig(100721697) protein phosphatase 1, catalytic subunit, alpha isozyme
  • sheep(101119264) protein phosphatase 1, catalytic subunit, alpha isozyme
  • Horse(100059233) protein phosphatase 1, catalytic subunit, alpha isozyme
  • dog(403609) protein phosphatase 1, catalytic subunit, alpha isozyme
  • naked mole-rat(101705408) protein phosphatase 1, catalytic subunit, alpha isozyme
  • domestic cat(101080405) protein phosphatase 1, catalytic subunit, alpha isozyme
  • cow(516175) protein phosphatase 1, catalytic subunit, alpha isozyme
  • Domestic Rabbit(100009298) protein phosphatase 1, catalytic subunit, alpha isozyme

Custom & Knockdown Gene Products

Antibodies

产品编号
说明
物种反应性
应用
Anti-ZAP-70 Antibody, clone 1E7.2, clone 1E7.2, Upstate®, from mouse,
物种反应性
human, mouse
应用
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-PPP1CA Antibody, clone 5E9, ascites fluid, clone 5E9, from mouse,
物种反应性
human
应用
western blot

Proteins

产品编号
说明
物种
PP1α 蛋白,10 µg, Recombinant, full length, human PP1α, for use in Phosphatase Assays.,
物种
human