PHOX2A
paired-like homeobox 2a
别名:
ARIX, CFEOM2, FEOM2, NCAM2, PMX2A
物种:
Human PHOX2A (401), Mouse Phox2a (11859), Rat Phox2a (116648), naked mole-rat Phox2a (101698435), Zebrafish phox2a (404602), chicken PHOX2A (395595), dog PHOX2A (485208), domestic cat PHOX2A (101095370), sheep PHOX2A (101103348), cow PHOX2A (507670)
UniProtKB ID:
基因ID:
- Human(401) Summary: The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq, Jul 2008]
- Mouse(11859) paired-like homeobox 2a
- Rat(116648) paired-like homeobox 2a
- naked mole-rat(101698435) paired-like homeobox 2a
- Zebrafish(404602) paired-like homeobox 2a
- chicken(395595) paired-like homeobox 2a
- dog(485208) paired-like homeobox 2a
- domestic cat(101095370) paired-like homeobox 2a
- sheep(101103348) paired-like homeobox 2a
- cow(507670) paired-like homeobox 2a
- domestic guinea pig(100732349) paired-like homeobox 2a
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Antibodies
产品编号
说明
物种反应性
应用
Anti-PHOX2A Antibody, from rabbit, purified by affinity chromatography,
物种反应性
human, rat
应用
immunohistochemistry
western blot
western blot