MBD3
methyl-CpG binding domain protein 3
别名:
物种:
Human MBD3 (53615), Mouse Mbd3 (17192), Rat Mbd3 (362834), domestic cat MBD3 (101098692), Thale Cress MBD3 (828069), chicken MBD3 (770153), dog MBD3 (485080), sheep MBD3 (101119469), naked mole-rat Mbd3 (101696358), cow MBD3 (616090)
UniProtKB ID:
基因ID:
- Human(53615) Summary: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). However, unlike the other family members, MBD3 is not capable of binding to methylated DNA. The predicted MBD3 protein shares 71% and 94% identity with MBD2 (isoform 1) and mouse Mbd3. MBD3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. MBD3 mediates the association of metastasis-associated protein 2 (MTA2) with the core histone deacetylase complex. [provided by RefSeq, Jul 2008]
- Mouse(17192) methyl-CpG binding domain protein 3
- Rat(362834) methyl-CpG binding domain protein 3
- domestic cat(101098692) methyl-CpG binding domain protein 3
- Thale Cress(828069) methyl-CpG-binding domain-containing protein 3
- chicken(770153) methyl-CpG binding domain protein 3
- dog(485080) methyl-CpG binding domain protein 3
- sheep(101119469) methyl-CpG binding domain protein 3
- naked mole-rat(101696358) methyl-CpG binding domain protein 3
- cow(616090) methyl-CpG binding domain protein 3
- domestic guinea pig(100713224) methyl-CpG binding domain protein 3
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Anti-MBD3 Antibody, clone 1K19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey, mouse, rat
应用
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-MBD3 antibody produced in rabbit, ,
物种反应性
mouse, rat
应用
immunohistochemistry
western blot
western blot