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Merck

MAPK7

mitogen-activated protein kinase 7

别名:
BMK1, ERK4, ERK5, PRKM7
物种:
UniProtKB ID:
基因ID:
  • Human(5598) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(23939) mitogen-activated protein kinase 7
  • Rat(114509) mitogen-activated protein kinase 7
  • Zebrafish(541323) mitogen-activated protein kinase 7
  • domestic cat(101097357) mitogen-activated protein kinase 7
  • cow(537703) mitogen-activated protein kinase 7
  • dog(489532) mitogen-activated protein kinase 7
  • Domestic Rabbit(100338535) mitogen-activated protein kinase 7
  • sheep(101110073) mitogen-activated protein kinase 7
  • naked mole-rat(101726391) mitogen-activated protein kinase 7
  • domestic guinea pig(100728396) mitogen-activated protein kinase 7

Custom & Knockdown Gene Products

Antibodies

产品编号
说明
物种反应性
应用
抗磷酸化-BMK1/Erk5 (Thr218/Tyr220) 抗体, Upstate®, from rabbit,
物种反应性
bovine, human, mouse, rat
应用
inhibition assay
western blot