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Merck

MAPK1

mitogen-activated protein kinase 1

别名:
ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk
物种:
UniProtKB ID:
基因ID:
  • Human(5594) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(26413) mitogen-activated protein kinase 1
  • Rat(116590) mitogen activated protein kinase 1
  • chicken(373953) mitogen-activated protein kinase 1
  • Zebrafish(360144) mitogen-activated protein kinase 1
  • dog(477575) mitogen-activated protein kinase 1
  • domestic cat(101087614) mitogen-activated protein kinase 1
  • sheep(101115485) mitogen-activated protein kinase 1
  • cow(327672) mitogen-activated protein kinase 1
  • naked mole-rat(101706099) mitogen-activated protein kinase 1
  • domestic guinea pig(100715180) mitogen-activated protein kinase 1

Custom & Knockdown Gene Products

Antibodies

产品编号
说明
物种反应性
应用
抗-MAPK 1/2抗体, from rabbit,
物种反应性
bovine, canine, human, mouse, rat
应用
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-phospho-MAP Kinase1/2 Antibody, clone 12D4, Upstate®, from mouse,
物种反应性
avian, canine, human, mouse, rat
应用
ELISA
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Milli-Mark® Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate, Milli-Mark®, from rabbit,
物种反应性
human
应用
flow cytometry
抗磷酸化-MAP激酶1/2 (Erk1/2)(Thr185/Tyr187) 抗体,克隆AW39, clone Aw39, Upstate®, from rabbit,
物种反应性
human, rat
应用
multiplexing
western blot