IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
别名:
IMPD2, IMPDH-II
物种:
Human IMPDH2 (3615), Mouse Impdh2 (23918), Rat Impdh2 (301005), dog IMPDH2 (476630), Zebrafish impdh2 (317745), domestic guinea pig Impdh2 (100730768), naked mole-rat Impdh2 (101701391), domestic cat IMPDH2 (101080693), cow IMPDH2 (511969), sheep IMPDH2 (101107823) ...展开
UniProtKB ID:
基因ID:
- Human(3615) Summary: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]
- Mouse(23918) inosine 5'-phosphate dehydrogenase 2
- Rat(301005) IMP (inosine 5'-monophosphate) dehydrogenase 2
- dog(476630) IMP (inosine 5'-monophosphate) dehydrogenase 2
- Zebrafish(317745) IMP (inosine monophosphate) dehydrogenase 2
- domestic guinea pig(100730768) IMP (inosine 5'-monophosphate) dehydrogenase 2
- naked mole-rat(101701391) IMP (inosine 5'-monophosphate) dehydrogenase 2
- domestic cat(101080693) IMP (inosine 5'-monophosphate) dehydrogenase 2
- cow(511969) IMP (inosine 5'-monophosphate) dehydrogenase 2
- sheep(101107823) IMP (inosine 5'-monophosphate) dehydrogenase 2
- Domestic Rabbit(100355621) IMP (inosine 5'-monophosphate) dehydrogenase 2
- chicken(416058) IMP (inosine 5'-monophosphate) dehydrogenase 2
- Horse(100063255) IMP (inosine 5'-monophosphate) dehydrogenase 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Anti-IMPDH2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-IMPDH2 antibody produced in mouse, clone 1E12-B6, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-IMPDH2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
immunofluorescence
western blot
western blot
Anti-IMPDH2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Small Molecule - Inhibitor
Proteins
货号
说明
物种