IL3RA
interleukin 3 receptor, alpha (low affinity)
CD123, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra
Human IL3RA (3563), Mouse Il3ra (16188), Rat Il3ra (246144), sheep IL3RA (101113991), dog IL3RA (609293), naked mole-rat Il3ra (101696721), cow IL3RA (100299249)
- Human(3563) Summary: The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012]
- Mouse(16188) interleukin 3 receptor, alpha chain
- Rat(246144) interleukin 3 receptor, alpha
- sheep(101113991) interleukin 3 receptor, alpha (low affinity)
- dog(609293) interleukin 3 receptor, alpha (low affinity)
- naked mole-rat(101696721) interleukin 3 receptor, alpha (low affinity)
- cow(100299249) interleukin 3 receptor, alpha (low affinity)
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Antibodies
Anti-IL3RA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunohistochemistry