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Merck

IKBKG

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

别名:
AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IP, IP1, IP2, IPD2, NEMO, ZC2HC9
物种:
UniProtKB ID:
基因ID:
  • Human(8517) Summary: This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Aug 2011]
  • Mouse(16151) inhibitor of kappaB kinase gamma
  • Rat(309295) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • Domestic Rabbit(100328905) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • domestic guinea pig(100722308) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • naked mole-rat(101712077) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • dog(612576) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • domestic cat(101086544) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • cow(281855) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • Zebrafish(541530) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • sheep(101107332) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

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Small Molecule - Antagonist

货号
说明
物种
小白菊内酯, ≥98% (HPLC),
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-IKBKG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
Anti-IKK-γ antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunohistochemistry

western blot
Anti-IKKγ antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunocytochemistry

western blot
Anti-IKKγ Antibody, Upstate®, from mouse,
物种反应性
human, mouse
应用
western blot
Anti-Phospho-IKKγ-S376 antibody produced in rabbit, ,
物种反应性
human, mouse
应用
immunohistochemistry
western blot

Proteins

货号
说明
物种
IKK-γ, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human IKBKG,
物种
human