IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
别名:
IDCD, IDH, IDP, IDPC, PICD
物种:
Human IDH1 (3417), Mouse Idh1 (15926), Rat Idh1 (24479), dog IDH1 (478889), Zebrafish idh1 (100006589), Thale Cress IDH1 (829679), domestic guinea pig Idh1 (100729107), chicken IDH1 (424112), Domestic Rabbit IDH1 (100328559), sheep IDH1 (443257) ...展开
UniProtKB ID:
基因ID:
- Human(3417) Summary: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. [provided by RefSeq, Jul 2008]
- Mouse(15926) isocitrate dehydrogenase 1 (NADP+), soluble
- Rat(24479) isocitrate dehydrogenase 1 (NADP+), soluble
- dog(478889) isocitrate dehydrogenase 1 (NADP+), soluble
- Zebrafish(100006589) isocitrate dehydrogenase 1 (NADP+), soluble
- Thale Cress(829679) Isocitrate dehydrogenase [NAD] regulatory subunit 1
- domestic guinea pig(100729107) isocitrate dehydrogenase 1 (NADP+), soluble
- chicken(424112) isocitrate dehydrogenase 1 (NADP+), soluble
- Domestic Rabbit(100328559) isocitrate dehydrogenase 1 (NADP+), soluble
- sheep(443257) isocitrate dehydrogenase 1 (NADP+), soluble
- cow(281235) isocitrate dehydrogenase 1 (NADP+), soluble
- Horse(100066416) isocitrate dehydrogenase 1 (NADP+), soluble
- domestic cat(751618) isocitrate dehydrogenase 1 (NADP+), soluble
- naked mole-rat(101705662) isocitrate dehydrogenase 1 (NADP+), soluble
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Antibodies
货号
说明
物种反应性
应用
小鼠单克隆抗 IDH1 (R132H) 抗体, clone HMab-1, purified from hybridoma cell culture,
物种反应性
human
应用
western blot
Anti-IDH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
抗-异柠檬酸脱氢酶1（IDH1）-R132H抗体，克隆HMab-1, clone HMab-1, from mouse,
物种反应性
human
应用
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
抗-IDH1 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
western blot
Kits
货号
说明
物种