HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
别名:
HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78
物种:
Human HIF1A (3091), Mouse Hif1a (15251), Rat Hif1a (29560), dog HIF1A (480348), domestic guinea pig Hif1a (100713113), naked mole-rat Hif1a (101715845), Domestic Rabbit HIF1A (100009579), sheep HIF1A (443519), cow HIF1A (281814), domestic cat HIF1A (101083686)
UniProtKB ID:
基因ID:
- Human(3091) Summary: This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]
- Mouse(15251) hypoxia inducible factor 1, alpha subunit
- Rat(29560) hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- dog(480348) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- domestic guinea pig(100713113) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- naked mole-rat(101715845) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- Domestic Rabbit(100009579) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- sheep(443519) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- cow(281814) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- domestic cat(101083686) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- chicken(374177) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
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ELISA
货号
说明
物种
Human HIF-1 alpha ELISA Kit, for cell culture supernatants, plasma, and serum samples,
物种
human
Antibodies
货号
说明
物种反应性
应用
Anti-HIF-1α Antibody, clone 2B14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey
应用
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
抗-HIF1A 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
抗缺氧诱导因子1 α 抗体，克隆 H1α67, clone H1alpha67, Chemicon®, from mouse,
物种反应性
ferret, human, mouse, rat
应用
electrophoretic mobility shift assay
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
抗-HIF1A 兔抗, ,
物种反应性
bovine, human, mouse, rat
应用
ChIP
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-HIF-1 alpha antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM242, purified immunoglobulin,
物种反应性
human
应用
immunohistochemistry
western blot
western blot