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Merck

GSTM3

glutathione S-transferase mu 3 (brain)

别名:
GST5, GSTB, GSTM3-3, GTM3
物种:
UniProtKB ID:
基因ID:
  • Human(2947) Summary: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]
  • Mouse(14864) glutathione S-transferase, mu 3
  • Rat(57298) glutathione S-transferase mu 3
  • naked mole-rat(101708562) glutathione S-transferase mu 3 (brain)
  • cow(615507) glutathione S-transferase mu 3 (brain)
  • domestic cat(100169963) glutathione S-transferase mu 3 (brain)
  • dog(479911) glutathione S-transferase mu 3 (brain)
  • Zebrafish(568744) glutathione S-transferase M3 (brain)

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Antibodies

货号
说明
物种反应性
应用
Anti-GSTM3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry

Cell Lines

货号
说明
物种
GST M3-3, Recombinant Human, ,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Gstm3,
物种
mouse
MISSION® esiRNA, targeting human GSTM3,
物种
human