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Merck

ERVW-1

endogenous retrovirus group W, member 1

别名:
ENV, ENVW, ERVWE1, HERV-7q, HERV-W-ENV, HERV7Q, HERVW, HERVWENV
物种:
UniProtKB ID:
基因ID:
  • Human(30816) Summary: Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]

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Antibodies

货号
说明
物种反应性
应用
Anti-ERVW-1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, rat
应用
western blot
Anti-ERVW-1 (N-terminal) antibody produced in rabbit HRP conjugated, affinity isolated antibody,
物种反应性
human, rat
应用
Anti-ERVW-1 (N-terminal) antibody produced in rabbit FITC conjugated, affinity isolated antibody,
物种反应性
human, rat
应用
Anti-ERVW-1 (N-terminal) antibody produced in rabbit biotin conjugated, affinity isolated antibody,
物种反应性
human, rat
应用

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human ERVW-1,
物种
human