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Merck

EIF2S1

eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa

别名:
EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A
物种:
Human EIF2S1 (1965), Mouse Eif2s1 (13665), Rat Eif2s1 (54318), chicken EIF2S1 (423279), Goat EIF2S1 (100861133), domestic cat EIF2S1 (101091455), sheep EIF2S1 (101113414), domestic guinea pig Eif2s1 (100716377), cow EIF2S1 (327694), dog EIF2S1 (480361)
UniProtKB ID:
P05198
基因ID:
  • Human(1965) Summary: The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]
  • Mouse(13665) eukaryotic translation initiation factor 2, subunit 1 alpha
  • Rat(54318) eukaryotic translation initiation factor 2, subunit 1 alpha
  • chicken(423279) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • Goat(100861133) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • domestic cat(101091455) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • sheep(101113414) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • domestic guinea pig(100716377) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • cow(327694) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • dog(480361) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • naked mole-rat(101723170) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa

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Antibodies

货号
说明
物种反应性
应用
SAB4504388
Anti-phospho-eIF2 α (pSer51) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
SAB4500729
Anti-EIF2 α antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
western blot
WH0001965M1
Monoclonal Anti-EIF2S1 antibody produced in mouse, clone 3H12-C11, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence
western blot
SAB4300221
Anti-phospho-EIF2S1 (pSer51) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
western blot
ZRB1560
Anti-eIF-2α Antibody, clone 3M6 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human
应用
affinity binding assay
flow cytometry
immunocytochemistry
western blot

Proteins

货号
说明
物种
SRP5232
EIF2S1, His tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
EHU054441
MISSION® esiRNA, targeting human EIF2S1,
物种
human
EMU003851
MISSION® esiRNA, targeting mouse Eif2s1,
物种
mouse