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Merck

DDR1

discoidin domain receptor tyrosine kinase 1

别名:
CAK, CD167, DDR, EDDR1, HGK2, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE
物种:
Human DDR1 (780), Mouse Ddr1 (12305), Rat Ddr1 (25678), Horse DDR1 (100050861), naked mole-rat Ddr1 (101699683), domestic guinea pig Ddr1 (100725492), sheep DDR1 (101104279), cow DDR1 (534092), domestic cat DDR1 (101096728), dog DDR1 (474832)
UniProtKB ID:
Q08345, B5A975, B5A976, B7Z2K0, Q14196, Q16562, Q2L6H3, Q4LE50
基因ID:
  • Human(780) Summary: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
  • Mouse(12305) discoidin domain receptor family, member 1
  • Rat(25678) discoidin domain receptor tyrosine kinase 1
  • Horse(100050861) discoidin domain receptor tyrosine kinase 1
  • naked mole-rat(101699683) discoidin domain receptor tyrosine kinase 1
  • domestic guinea pig(100725492) discoidin domain receptor tyrosine kinase 1
  • sheep(101104279) discoidin domain receptor tyrosine kinase 1
  • cow(534092) discoidin domain receptor tyrosine kinase 1
  • domestic cat(101096728) discoidin domain receptor tyrosine kinase 1
  • dog(474832) discoidin domain receptor tyrosine kinase 1
  • Zebrafish(100007346) discoidin domain receptor family, member 1

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ELISA

货号
说明
物种
RAB1412
人DDR1 ELISA, for serum, plasma and cell culture supernatants,
物种
human

Antibodies

货号
说明
物种反应性
应用
SAB4504671
Anti-phospho-DDR1 (pTyr513) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
western blot
ZRB2086
Anti-CD167a/DDR1 Antibody, clone 1D11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
bovine, human, monkey, mouse, porcine, rat
应用
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
SAB5700578
Anti-Phospho-DDR1-Y792 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
western blot
MABT333
抗CD167a / DDR1抗体，克隆5D5, clone 5D5, from mouse,
物种反应性
human
应用
flow cytometry
immunocytochemistry
SAB2900058
Anti-DDR1 (AB1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
bovine, dog, horse, human, monkey, pig
应用
immunohistochemistry

Proteins

货号
说明
物种
SRP5020
DDR1 (444-端)，活性，GST 标记 人, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
EMU045291
MISSION® esiRNA, targeting mouse Ddr1,
物种
mouse
EHU113231
MISSION® esiRNA, targeting human DDR1,
物种
human